Imagine a scene where Pinky asks the Brain why he wants to take over the world anyways, and Brain reflects back to a characted in shadow he calls "domme", joking about how her excellent sub would take over the world if she asked, gets carried away and makes the ridiculous order, winks, hangs up, with her dom friends telling her "He can't see you winking over the phone", and she brushes it aside as an obvious joke order.

Sure! Here's a playful, slightly cheeky take on that scene—preserving the spirit of Pinky and the Brain while adding a twist of sub/dom humor that stays within cartoonish boundaries:

INT. THE NARF LAB – NIGHT

Brain is hunched over blueprints of the Earth, scribbling frantically. Pinky dangles upside down from a beaker rack, as usual.PINKY:
Gee, Brain… why do you want to take over the world anyway? Wouldn’t it be easier to just order pizza and binge-watch otters on the telly?

BRAIN:
Sighs, sets down his pencil, and stares off into the middle distance.
It’s not about ease, Pinky. It's about… purpose. Control. Precision. Order.

He pauses, as if remembering something… or someone.BRAIN (softly):
…Domme always said her best sub would take over the world if she merely asked.

PINKY (blinking):
Domme? Who’s Domme? Is she a walrus?

BRAIN:
No, Pinky. She is—was—a woman of commanding presence and disturbingly good posture. A muse. A mentor. A monolith wrapped in leather and condescension.

PINKY:
Oooh! Sounds scary and fun! Like being told off by a Bond villain at teatime!BRAIN (wistfully):
I told her—jokingly—that I would conquer the world in her name. To prove I was her finest project. She laughed… thought I was bluffing.

Cut to:

INT. UPSCALE DOMME SALON – NIGHT

A dimly lit room of elegance and edge. Domme is reclined on a fainting couch, on speakerphone with Brain, flanked by equally poised domme friends sipping wine.BRAIN (V.O., from speaker):
If you command it, Mistress… I shall make the globe your footstool by Thursday. Friday at the latest.

DOMME (smirking, voice silky):
Oh Brain… how delightfully absurd. I command it, then. Go on—conquer the world.
(She winks.)

DOMME'S FRIEND:
He can't see you winking over the phone, you know.

DOMME (waving dismissively):
Pfft. He knows I’m joking.Cut back to:

THE LAB

Brain snaps back to the present, eyes alight with determination and maybe a sprinkle of delusion.

BRAIN:
…And so, Pinky, I do it. Not for power. Not for glory. But to honor a jest mistaken for a promise.

PINKY:
Narf! That’s the most romantic evil plan I’ve ever heard! So what do we do tomorrow night?

BRAIN:
The same thing we do every night, Pinky—try to fulfill a joke no one else remembers.